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Allosteric Switching by Mutually Exclusive Folding of Protein Domains

Many proteins are built from structurally and functionally distinct and domains. A major goal is to understand how conformational change transmits information between domains in order to achieve biological activity. A two-domain, bi-functional fusion protein has been designed so that the mechanical...

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Detalhes bibliográficos
Main Authors: Radley, Tracy L., Markowska, Anna I., Bettinger, Blaine T., Ha, Jeung-Hoi, Loh, Stewart N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145375/
https://ncbi.nlm.nih.gov/pubmed/12963365
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