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Molecular Simulations of Mutually Exclusive Folding in a Two-Domain Protein Switch

A major challenge with testing designs of protein conformational switches is the need for experimental probes that can independently monitor their individual protein domains. One way to circumvent this issue is to use a molecular simulation approach in which each domain can be directly observed. Her...

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Autors principals: Mills, Brandon M., Chong, Lillian T.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030150/
https://ncbi.nlm.nih.gov/pubmed/21281591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.12.3710
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