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Construction of Allosteric Protein Switches by Alternate Frame Folding and Intermolecular Fragment Exchange
Alternate frame folding (AFF) and protein/fragment exchange (FREX) are related technologies for engineering allosteric conformational changes into proteins that have no pre-existing allosteric properties. One of their chief purposes is to turn an ordinary protein into a biomolecular switch capable o...
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| Pubblicato in: | Methods Mol Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538016/ https://ncbi.nlm.nih.gov/pubmed/28293878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6940-1_2 |
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