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Converting a Binding Protein into a Biosensing Conformational Switch Using Protein Fragment Exchange

[Image: see text] Biosensors can be used in applications ranging from identifying disease biomarkers to detecting spatial and temporal distributions of specific molecules in living cells. A major challenge facing biosensor development is how to functionally couple a biological recognition domain to...

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Autors principals: Zheng, Huimei, Bi, Jing, Krendel, Mira, Loh, Stewart N.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151334/
https://ncbi.nlm.nih.gov/pubmed/25084233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500758u
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