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Converting a protein into a switch for biosensing and functional regulation

Proteins that switch conformations in response to a signaling event (e.g., ligand binding or chemical modification) present a unique solution to the design of reagent-free biosensors as well as molecules whose biological functions are regulated in useful ways. The principal roadblock in the path to...

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Detalhes bibliográficos
Main Authors: Stratton, Margaret M, Loh, Stewart N
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047058/
https://ncbi.nlm.nih.gov/pubmed/21064163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.541
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