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Engineered Domain Swapping as an On/Off Switch for Protein Function

Domain swapping occurs when identical proteins exchange segments in reciprocal fashion. Natural swapping mechanisms remain poorly understood and engineered swapping has the potential for creating self-assembling biomaterials that encode for emergent functions. We demonstrate that induced swapping ca...

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Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Ha, Jeung-Hoi, Karchin, Joshua M., Walker-Kopp, Nancy, Castañeda, Carlos A., Loh, Stewart N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621486/
https://ncbi.nlm.nih.gov/pubmed/26496687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.09.007
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