Generation of Naivetropic Induced Pluripotent Stem Cells from Parkinson's Disease Patients for High-Efficiency Genetic Manipulation and Disease Modeling

The lack of robust Parkinson's disease (PD) phenotype in parkin knockout rodents and the identification of defective dopaminergic (DA) neurotransmission in midbrain DA neurons derived from induced pluripotent stem cells (iPSC) of PD patients with parkin mutations demonstrate the utility of pati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Stem Cells Dev
Prif Awduron: Hu, Zhixing, Pu, Jiali, Jiang, Houbo, Zhong, Ping, Qiu, Jingxin, Li, Feng, Wang, Xiaomin, Zhang, Baorong, Yan, Zhen, Feng, Jian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2015
Pynciau:
Original Research Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620536/
https://ncbi.nlm.nih.gov/pubmed/26218671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0079
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