Modeling Parkinson’s Disease Using Patient-specific Induced Pluripotent Stem Cells

Parkinson’s disease (PD) is the second most common neurodegenerative disorder. It is characterized by the degeneration of nigral dopaminergic (DA) neurons. While over 90% of cases are idiopathic, without a clear etiology, mutations in many genes have been linked to rare, familial forms of PD. It has...

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Bibliographic Details
Published in:J Parkinsons Dis
Main Authors: Li, Hong, Jiang, Houbo, Zhang, Boyang, Feng, Jian
Format: Artigo
Language:Inglês
Published: IOS Press 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218140/
https://ncbi.nlm.nih.gov/pubmed/30149462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-181353
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