Generation of Naivetropic Induced Pluripotent Stem Cells from Parkinson's Disease Patients for High-Efficiency Genetic Manipulation and Disease Modeling

The lack of robust Parkinson's disease (PD) phenotype in parkin knockout rodents and the identification of defective dopaminergic (DA) neurotransmission in midbrain DA neurons derived from induced pluripotent stem cells (iPSC) of PD patients with parkin mutations demonstrate the utility of pati...

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Publicado en:Stem Cells Dev
Autores principales: Hu, Zhixing, Pu, Jiali, Jiang, Houbo, Zhong, Ping, Qiu, Jingxin, Li, Feng, Wang, Xiaomin, Zhang, Baorong, Yan, Zhen, Feng, Jian
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Original Research Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620536/
https://ncbi.nlm.nih.gov/pubmed/26218671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0079
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