Generation of Naivetropic Induced Pluripotent Stem Cells from Parkinson's Disease Patients for High-Efficiency Genetic Manipulation and Disease Modeling

The lack of robust Parkinson's disease (PD) phenotype in parkin knockout rodents and the identification of defective dopaminergic (DA) neurotransmission in midbrain DA neurons derived from induced pluripotent stem cells (iPSC) of PD patients with parkin mutations demonstrate the utility of pati...

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Detalhes bibliográficos
Publicado no:Stem Cells Dev
Main Authors: Hu, Zhixing, Pu, Jiali, Jiang, Houbo, Zhong, Ping, Qiu, Jingxin, Li, Feng, Wang, Xiaomin, Zhang, Baorong, Yan, Zhen, Feng, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Research Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620536/
https://ncbi.nlm.nih.gov/pubmed/26218671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0079
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