Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

Fibrin(ogen) is central to hemostasis and thrombosis and also contributes to multiple physiologic and pathologic processes beyond coagulation. However, the precise contribution of soluble fibrinogen vs insoluble fibrin matrices to vascular integrity, tissue repair, inflammation, and disease has been...

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Vydáno v:Blood
Hlavní autoři: Prasad, Joni M., Gorkun, Oleg V., Raghu, Harini, Thornton, Sherry, Mullins, Eric S., Palumbo, Joseph S., Ko, Ya-Ping, Höök, Magnus, David, Tovo, Coughlin, Shaun R., Degen, Jay L., Flick, Matthew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2015
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616238/
https://ncbi.nlm.nih.gov/pubmed/26228483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-639849
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