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The αC domains of fibrinogen affect the structure of the fibrin clot, its physical properties, and its susceptibility to fibrinolysis

The functions of the αC domains of fibrinogen in clotting and fibrinolysis, which have long been enigmatic, were determined using recombinant fibrinogen truncated at Aα chain residue 251. Scanning electron microscopy and confocal microscopy revealed that the fibers of α251 clots were thinner and den...

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Detalhes bibliográficos
Main Authors: Collet, Jean-Philippe, Moen, Jennifer L., Veklich, Yuri I., Gorkun, Oleg V., Lord, Susan T., Montalescot, Gilles, Weisel, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895112/
https://ncbi.nlm.nih.gov/pubmed/16091450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-05-2150
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