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Functional impact of oxidative post-translational modifications on fibrinogen and fibrin clots

Fibrinogen is a circulating multifunctional plasma protein vital for hemostasis. Activation of the coagulation cascade converts soluble fibrinogen to insoluble polymerized fibrin, which, along with platelets, forms the hemostatic clot. However, inappropriate formation of fibrin clots may result in a...

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Autors principals: Martinez, Marissa, Weisel, John W., Ischiropoulos, Harry
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852169/
https://ncbi.nlm.nih.gov/pubmed/23851017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.06.039
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