Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury

Victims of trauma often develop impaired blood clot formation (coagulopathy) that contributes to bleeding and mortality. Fibrin polymerization is one critical component of clot formation that can be impacted by post-translational oxidative modifications of fibrinogen after exposure to oxidants. In v...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: White, Nathan J., Wang, Yi, Fu, Xiaoyun, Cardenas, Jessica C., Martin, Erika J., Brophy, Donald F., Wade, Charles E., Wang, Xu, St. John, Alexander E., Lim, Esther B., Stern, Susan A., Ward, Kevin R., López, José A., Chung, Dominic
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912420/
https://ncbi.nlm.nih.gov/pubmed/27105953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.04.023
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