The molecular origins of the mechanical properties of fibrin

Por Falvo, Michael R., Gorkun, Oleg V., Lord, Susan T.
Publicado em 2010

Identification of the Staphylococcus aureus MSCRAMM clumping factor B (ClfB) binding site in the αC-domain of human fibrinogen

Por Walsh, Evelyn J., Miajlovic, Helen, Gorkun, Oleg V., Foster, Timothy J.
Publicado em 2008

Kinetics of the Multistep Rupture of Fibrin ‘A-a’ Polymerization Interactions Measured Using Atomic Force Microscopy

Por Averett, Laurel E., Schoenfisch, Mark H., Akhremitchev, Boris B., Gorkun, Oleg V.
Publicado em 2009

Substitution of the human αC region with the analogous chicken domain generates a fibrinogen with severely impaired lateral aggregation: fibrin monomers assemble into protofibrils...

Por Ping, Lifang, Huang, Lihong, Cardinali, Barbara, Profumo, Aldo, Gorkun, Oleg V., Lord, Susan T.
Publicado em 2011

Polymerization of fibrin: specificity, strength, and stability of knob-hole interactions studied at the single-molecule level

Por Litvinov, Rustem I., Gorkun, Oleg V., Owen, Scott F., Shuman, Henry, Weisel, John W.
Publicado em 2005

Direct evidence for specific interactions of the fibrinogen αC-domains with the central E region and with each other

Por Litvinov, Rustem I., Yakovlev, Sergiy, Tsurupa, Galina, Gorkun, Oleg V., Medved, Leonid, Weisel, John W.
Publicado em 2007

The Interaction of Integrin α(IIb)β(3) with Fibrin Occurs through Multiple Binding Sites in the α(IIb) β-Propeller Domain

Por Podolnikova, Nataly P., Yakovlev, Sergiy, Yakubenko, Valentin P., Wang, Xu, Gorkun, Oleg V., Ugarova, Tatiana P.
Publicado em 2014

Polymerization of fibrin: direct observation and quantification of individual B:b knob-hole interactions

Por Litvinov, Rustem I., Gorkun, Oleg V., Galanakis, Dennis K., Yakovlev, Sergiy, Medved, Leonid, Shuman, Henry, Weisel, John W.
Publicado em 2007

The αC domains of fibrinogen affect the structure of the fibrin clot, its physical properties, and its susceptibility to fibrinolysis

Por Collet, Jean-Philippe, Moen, Jennifer L., Veklich, Yuri I., Gorkun, Oleg V., Lord, Susan T., Montalescot, Gilles, Weisel, John W.
Publicado em 2005

The Assembly of Nonadhesive Fibrinogen Matrices Depends on the αC Regions of the Fibrinogen Molecule

Por Yermolenko, Ivan S., Gorkun, Oleg V., Fuhrmann, Alexander, Podolnikova, Nataly P., Lishko, Valeryi K., Oshkadyerov, Stanislav P., Lord, Susan T., Ros, Robert, Ugarova, Tatiana P.
Publicado em 2012

Submillisecond Elastic Recoil Reveals Molecular Origins of Fibrin Fiber Mechanics

Por Hudson, Nathan E., Ding, Feng, Bucay, Igal, O’Brien, E. Timothy, Gorkun, Oleg V., Superfine, Richard, Lord, Susan T., Dokholyan, Nikolay V., Falvo, Michael R.
Publicado em 2013

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

Por Prasad, Joni M., Gorkun, Oleg V., Raghu, Harini, Thornton, Sherry, Mullins, Eric S., Palumbo, Joseph S., Ko, Ya-Ping, Höök, Magnus, David, Tovo, Coughlin, Shaun R., Degen, Jay L., Flick, Matthew J.
Publicado no Blood (2015)