Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

Fibrin(ogen) is central to hemostasis and thrombosis and also contributes to multiple physiologic and pathologic processes beyond coagulation. However, the precise contribution of soluble fibrinogen vs insoluble fibrin matrices to vascular integrity, tissue repair, inflammation, and disease has been...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Prasad, Joni M., Gorkun, Oleg V., Raghu, Harini, Thornton, Sherry, Mullins, Eric S., Palumbo, Joseph S., Ko, Ya-Ping, Höök, Magnus, David, Tovo, Coughlin, Shaun R., Degen, Jay L., Flick, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616238/
https://ncbi.nlm.nih.gov/pubmed/26228483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-639849
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