Učitavanje...

The Interaction of Integrin α(IIb)β(3) with Fibrin Occurs through Multiple Binding Sites in the α(IIb) β-Propeller Domain

The currently available antithrombotic agents target the interaction of platelet integrin α(IIb)β(3) (GPIIb-IIIa) with fibrinogen during platelet aggregation. Platelets also bind fibrin formed early during thrombus growth. It was proposed that inhibition of platelet-fibrin interactions may be a nece...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Podolnikova, Nataly P., Yakovlev, Sergiy, Yakubenko, Valentin P., Wang, Xu, Gorkun, Oleg V., Ugarova, Tatiana P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900980/
https://ncbi.nlm.nih.gov/pubmed/24338009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518126
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!