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Leukocyte integrin Mac-1 (CD11b/CD18, α(M)β(2), CR3) acts as a functional receptor for platelet factor 4

Platelet factor 4 (PF4) is one of the most abundant cationic proteins secreted from α-granules of activated platelets. Based on its structure, PF4 was assigned to the CXC family of chemokines and has been shown to have numerous effects on myeloid leukocytes. However, the receptor for PF4 remains unk...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lishko, Valeryi K., Yakubenko, Valentin P., Ugarova, Tatiana P., Podolnikova, Nataly P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936813/
https://ncbi.nlm.nih.gov/pubmed/29540475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000515
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