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Leukocyte integrin Mac-1 (CD11b/CD18, α(M)β(2), CR3) acts as a functional receptor for platelet factor 4

Platelet factor 4 (PF4) is one of the most abundant cationic proteins secreted from α-granules of activated platelets. Based on its structure, PF4 was assigned to the CXC family of chemokines and has been shown to have numerous effects on myeloid leukocytes. However, the receptor for PF4 remains unk...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Lishko, Valeryi K., Yakubenko, Valentin P., Ugarova, Tatiana P., Podolnikova, Nataly P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936813/
https://ncbi.nlm.nih.gov/pubmed/29540475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000515
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