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The Role of Integrins α(M)β(2) (Mac-1, CD11b/CD18) and α(D)β(2) (CD11d/CD18) in Macrophage Fusion

The subfamily of β2 integrins is implicated in macrophage fusion, a hallmark of chronic inflammation. Among β2 family members, integrin Mac-1 (α(M)β(2), CD11b/CD18) is abundantly expressed on monocyte/macrophages and mediates critical adhesive reactions of these cells. However, the role of Mac-1 in...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Podolnikova, Nataly P., Kushchayeva, Yevgeniya S., Wu, YiFei, Faust, James, Ugarova, Tatiana P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973655/
https://ncbi.nlm.nih.gov/pubmed/27315778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.04.001
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