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Ligand Recognition Specificity of Leukocyte Integrin α(M)β(2) (Mac-1, CD11b/CD18) and Its Functional Consequences
The broad recognition specificity exhibited by integrin α(M)β(2) (Mac-1, CD11b/CD18) has allowed this adhesion receptor to play innumerable roles in leukocyte biology, yet we know little about how and why α(M)β(2) binds its multiple ligands. Within α(M)β(2), the α(M)I-domain is responsible for integ...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532391/ https://ncbi.nlm.nih.gov/pubmed/25613106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5013782 |
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