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Ligand Recognition Specificity of Leukocyte Integrin α(M)β(2) (Mac-1, CD11b/CD18) and Its Functional Consequences

The broad recognition specificity exhibited by integrin α(M)β(2) (Mac-1, CD11b/CD18) has allowed this adhesion receptor to play innumerable roles in leukocyte biology, yet we know little about how and why α(M)β(2) binds its multiple ligands. Within α(M)β(2), the α(M)I-domain is responsible for integ...

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書誌詳細
出版年:Biochemistry
主要な著者: Podolnikova, Nataly P., Podolnikov, Andriy V., Haas, Thomas A., Lishko, Valeryi K., Ugarova, Tatiana P.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532391/
https://ncbi.nlm.nih.gov/pubmed/25613106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5013782
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