The Interaction of Integrin α(IIb)β(3) with Fibrin Occurs through Multiple Binding Sites in the α(IIb) β-Propeller Domain

The currently available antithrombotic agents target the interaction of platelet integrin α(IIb)β(3) (GPIIb-IIIa) with fibrinogen during platelet aggregation. Platelets also bind fibrin formed early during thrombus growth. It was proposed that inhibition of platelet-fibrin interactions may be a nece...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Podolnikova, Nataly P., Yakovlev, Sergiy, Yakubenko, Valentin P., Wang, Xu, Gorkun, Oleg V., Ugarova, Tatiana P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900980/
https://ncbi.nlm.nih.gov/pubmed/24338009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.518126
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker