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Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis

Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Wang, Jiaolong, Chen, Li, Chen, Bohao, Meliton, Angelo, Liu, Shu Q., Shi, Yongyan, Liu, Tianjing, Deb, Dilip K., Solway, Julian, Chun Li, Yan
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4616037/
https://ncbi.nlm.nih.gov/pubmed/26494430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15561
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