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Vitamin D Receptor Attenuates Renal Fibrosis by Suppressing the Renin-Angiotensin System
Analogs of vitamin D attenuate renal injury in several models of kidney disease, but the mechanism underlying this renoprotective effect is unknown. To address the role of the vitamin D receptor (VDR) in renal fibrogenesis, we subjected VDR-null mice to unilateral ureteral obstruction for 7 days. Co...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900963/ https://ncbi.nlm.nih.gov/pubmed/20378820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009080872 |
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