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Vitamin D Receptor Attenuates Renal Fibrosis by Suppressing the Renin-Angiotensin System

Analogs of vitamin D attenuate renal injury in several models of kidney disease, but the mechanism underlying this renoprotective effect is unknown. To address the role of the vitamin D receptor (VDR) in renal fibrogenesis, we subjected VDR-null mice to unilateral ureteral obstruction for 7 days. Co...

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Detalhes bibliográficos
Main Authors: Zhang, Yan, Kong, Juan, Deb, Dilip K., Chang, Anthony, Li, Yan Chun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900963/
https://ncbi.nlm.nih.gov/pubmed/20378820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009080872
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