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Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis
Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4616037/ https://ncbi.nlm.nih.gov/pubmed/26494430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15561 |
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