VDR Attenuates Acute Lung Injury by Blocking Ang-2-Tie-2 Pathway and Renin-Angiotensin System

Acute lung injury (ALI) is a hallmark of systemic inflammation associated with high mortality. Although the vitamin D receptor (VDR) is highly expressed in the lung, its role in lung physiology remains unclear. We investigated the effect of VDR deletion on ALI using a lipopolysaccharide (LPS)-induce...

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Detalhes bibliográficos
Main Authors: Kong, Juan, Zhu, Xiangdong, Shi, Yongyan, Liu, Tianjing, Chen, Yunzi, Bhan, Ishir, Zhao, Qun, Thadhani, Ravi, Li, Yan Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857197/
https://ncbi.nlm.nih.gov/pubmed/24196349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1146
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