Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence

Cellular senescence, the stable cell cycle arrest elicited by various forms of stress, is an important facet of tumor suppression. Although much is known about the key players in the implementation of senescence, including the pRb and p53 axes and the cyclin dependent kinase inhibitors p16(INK4a) an...

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Foilsithe in:Cell Cycle
Main Authors: Brookes, Sharon, Gagrica, Sladjana, Sanij, Elaine, Rowe, Janice, Gregory, Fiona J, Hara, Eiji, Peters, Gordon
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2015
Ábhair:
Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613988/
https://ncbi.nlm.nih.gov/pubmed/25695870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1010866
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