Cargando...
Contrasting behavior of the p18(INK4c) and p16(INK4a) tumor suppressors in both replicative and oncogene-induced senescence
The CDK inhibitors, p18(INK4c) and p16(INK4a), both have the credentials of tumor suppressors in human cancers and mouse models. For p16(INK4a), the underlying rationale is its role in senescence but the selective force for inactivation of p18(INK4c) in incipient cancer cells is less clear. Here we...
Gardado en:
| Publicado en: | Cancer Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248231/ https://ncbi.nlm.nih.gov/pubmed/22080569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2552 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|