GABA(B) Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

Autism spectrum disorder (ASD) is diagnosed by two core behavioral criteria, unusual reciprocal social interactions and communication, and stereotyped, repetitive behaviors with restricted interests. Excitatory/inhibitory imbalance is a prominent hypothesis for the etiology of autism. The selective...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuropsychopharmacology
Main Authors: Silverman, J L, Pride, M C, Hayes, J E, Puhger, K R, Butler-Struben, H M, Baker, S, Crawley, J N
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613612/
https://ncbi.nlm.nih.gov/pubmed/25754761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.66
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