GABA(B) Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

Autism spectrum disorder (ASD) is diagnosed by two core behavioral criteria, unusual reciprocal social interactions and communication, and stereotyped, repetitive behaviors with restricted interests. Excitatory/inhibitory imbalance is a prominent hypothesis for the etiology of autism. The selective...

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Dettagli Bibliografici
Pubblicato in:Neuropsychopharmacology
Autori principali: Silverman, J L, Pride, M C, Hayes, J E, Puhger, K R, Butler-Struben, H M, Baker, S, Crawley, J N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613612/
https://ncbi.nlm.nih.gov/pubmed/25754761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.66
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