GABA(B) Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

Autism spectrum disorder (ASD) is diagnosed by two core behavioral criteria, unusual reciprocal social interactions and communication, and stereotyped, repetitive behaviors with restricted interests. Excitatory/inhibitory imbalance is a prominent hypothesis for the etiology of autism. The selective...

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Dades bibliogràfiques
Publicat a:Neuropsychopharmacology
Autors principals: Silverman, J L, Pride, M C, Hayes, J E, Puhger, K R, Butler-Struben, H M, Baker, S, Crawley, J N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613612/
https://ncbi.nlm.nih.gov/pubmed/25754761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.66
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