GABA(B) Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

Autism spectrum disorder (ASD) is diagnosed by two core behavioral criteria, unusual reciprocal social interactions and communication, and stereotyped, repetitive behaviors with restricted interests. Excitatory/inhibitory imbalance is a prominent hypothesis for the etiology of autism. The selective...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Silverman, J L, Pride, M C, Hayes, J E, Puhger, K R, Butler-Struben, H M, Baker, S, Crawley, J N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613612/
https://ncbi.nlm.nih.gov/pubmed/25754761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.66
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