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GABA(B)-Agonistic Activity of Certain Baclofen Homologues
Baclofen (1) is a potent and selective agonist for bicuculline-insensitive GABA(B) receptors and is used clinically as an antispastic and muscle relaxant agent. In the search for new bioactive chemical entities that bind specifically to GABA(B) receptors, we report here the synthesis of certain bacl...
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| Publicado no: | Molecules |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6270091/ https://ncbi.nlm.nih.gov/pubmed/23973998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180910266 |
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