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GABA(B)-Agonistic Activity of Certain Baclofen Homologues

Baclofen (1) is a potent and selective agonist for bicuculline-insensitive GABA(B) receptors and is used clinically as an antispastic and muscle relaxant agent. In the search for new bioactive chemical entities that bind specifically to GABA(B) receptors, we report here the synthesis of certain bacl...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Attia, Mohamed I., Herdeis, Claus, Bräuner-Osborne, Hans
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270091/
https://ncbi.nlm.nih.gov/pubmed/23973998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180910266
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