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Baclofen, an agonist at peripheral GABA(B) receptors, induces antinociception via activation of TEA-sensitive potassium channels
BACKGROUND AND PURPOSE: Central anti-nociceptive actions of baclofen involve activation of K(+) channels. Here we assessed what types of K(+) channel might participate in the peripheral anti-nociception induced by baclofen. EXPERIMENTAL APPROACH: Nociceptive thresholds to mechanical stimulation in r...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014648/ https://ncbi.nlm.nih.gov/pubmed/17016510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706898 |
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