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Baclofen, an agonist at peripheral GABA(B) receptors, induces antinociception via activation of TEA-sensitive potassium channels

BACKGROUND AND PURPOSE: Central anti-nociceptive actions of baclofen involve activation of K(+) channels. Here we assessed what types of K(+) channel might participate in the peripheral anti-nociception induced by baclofen. EXPERIMENTAL APPROACH: Nociceptive thresholds to mechanical stimulation in r...

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Main Authors: Reis, G M L, Duarte, I D G
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014648/
https://ncbi.nlm.nih.gov/pubmed/17016510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706898
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