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GABA(B)-Agonistic Activity of Certain Baclofen Homologues

Baclofen (1) is a potent and selective agonist for bicuculline-insensitive GABA(B) receptors and is used clinically as an antispastic and muscle relaxant agent. In the search for new bioactive chemical entities that bind specifically to GABA(B) receptors, we report here the synthesis of certain bacl...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Attia, Mohamed I., Herdeis, Claus, Bräuner-Osborne, Hans
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6270091/
https://ncbi.nlm.nih.gov/pubmed/23973998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules180910266
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