GABA(B) Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

Autism spectrum disorder (ASD) is diagnosed by two core behavioral criteria, unusual reciprocal social interactions and communication, and stereotyped, repetitive behaviors with restricted interests. Excitatory/inhibitory imbalance is a prominent hypothesis for the etiology of autism. The selective...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuropsychopharmacology
Hlavní autoři: Silverman, J L, Pride, M C, Hayes, J E, Puhger, K R, Butler-Struben, H M, Baker, S, Crawley, J N
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613612/
https://ncbi.nlm.nih.gov/pubmed/25754761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.66
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky