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Phosphorylation of FE65 Ser(610) by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing
Alzheimer's disease (AD) is a fatal neurodegenerative disease affecting 36 million people worldwide. Genetic and biochemical research indicate that the excessive generation of amyloid-β peptide (Aβ) from amyloid precursor protein (APP), is a major part of AD pathogenesis. FE65 is a brain-enrich...
Kaydedildi:
| Yayımlandı: | Biochem J |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Portland Press Ltd.
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613528/ https://ncbi.nlm.nih.gov/pubmed/26188042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141485 |
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