Dexras1 Interacts with FE65 to Regulate FE65-Amyloid Precursor Protein-dependent Transcription

FE65 is an adaptor protein that binds to and forms a transcriptionally active complex with the γ-secretase-derived amyloid precursor protein (APP) intracellular domain. The regulatory mechanisms of FE65-APP-mediated transcription are still not clear. In this report, we demonstrate that Dexras1, a Ra...

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Main Authors: Lau, Kwok-Fai, Chan, Wing-Man, Perkinton, Michael S., Tudor, Elizabeth L., Chang, Raymond C. C., Chan, H.-Y. Edwin, McLoughlin, Declan M., Miller, Christopher C. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259905/
https://ncbi.nlm.nih.gov/pubmed/18922798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801874200
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