Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1

Neurite outgrowth is a crucial process in developing neurons for neural network formation. Understanding the regulatory mechanisms of neurite outgrowth is essential for developing strategies to stimulate neurite regeneration after nerve injury and in neurodegenerative disorders. FE65 is a brain-enri...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Li, Wen, Tam, Ka Ming Vincent, Chan, Wai Wa Ray, Koon, Alex Chun, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin, Lau, Kwok-Fai
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961050/
https://ncbi.nlm.nih.gov/pubmed/29615491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000505
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