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Construction, expression and tumor targeting of a single-chain Fv against human colorectal carcinoma
AIM: A single-chain antibody fragment, ND-1scFv, against human colorectal carcinoma was constructed and expressed in E.coli, and its biodistribution and pharmacokinetic properties were studied in mice bearing tumor. METHODS: V(H) and V(L) genes were amplified from hybridoma cell IC-2, secreting mono...
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| I publikationen: | World J Gastroenterol |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Baishideng Publishing Group Inc
2003
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611438/ https://ncbi.nlm.nih.gov/pubmed/12679920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v9.i4.726 |
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