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Tumor Targeting by a Multivalent Single-Chain Fv (scFv) Anti-Lewis Y Antibody Construct

The use of single-chain variable fragment (scFv) constructs has been investigated in cancer radioimmunotherapy (RIT) and radioimmunodetection, as these molecules permit rapid tumor penetration and clearance from the serum relative to whole IgG. Multimerization of scFv constructs has demonstrated imp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kelly, Marcus P., Lee, F.-T., Tahtis, Kiki, Power, Barbara E., Smyth, Fiona E., Brechbiel, Martin W., Hudson, Peter J., Scott, Andrew M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663784/
https://ncbi.nlm.nih.gov/pubmed/18771345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2007.0450
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