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Construction of non-covalent single-chain Fv dimers for hepatocellular carcinoma and their biological functions
AIM: To create new diabodies with improved binding activity to antigen of the variable light - variable heavy (VH-VL) oriented single-chain Fv dimers genes (scFv). METHODS: The linker between VH and VL genes was shortened to 3-5 amino acid residues and cloned into the vector pCANTAB5E. The recombina...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998965/ https://ncbi.nlm.nih.gov/pubmed/21160994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v2.i5.185 |
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