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Primary targeting of recombinant Fv-immunotoxin hscFv(25)-mTNFα against hepatocellular carcinoma
AIM: To obtain human recombinant Fv-immunotoxin hscFv(25)-mTNFα (mutant human TNFα fused to human scFv(25)) against hepatocellular carcinoma (HCC). METHODS: Two relevant sites of enzymatic digestion were added to mTNFα by PCR. mTNFα was linked to the 3’ end of hscFv(25) in pGEX4T-1 vector. This anti...
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| Опубликовано в: : | World J Gastroenterol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Inc
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572220/ https://ncbi.nlm.nih.gov/pubmed/15222026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i13.1872 |
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