A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
B3(dsFv)-PE38KDEL is a recombinant immunotoxin composed of the Fv region of monoclonal antibody B3 connected to a truncated form of Pseudomonas exotoxin (PE38KDEL), in which the unstable Fv heterodimer (composed of heavy- and light-chain variable regions) is held together and stabilized by a disulfi...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47177/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7538 |
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