Independent domain folding of Pseudomonas exotoxin and single-chain immunotoxins: influence of interdomain connections.
We have studied the refolding of completely unfolded and reduced Pseudomonas exotoxin (PE) and of recombinant single-chain immunotoxins made with monoclonal antibody B3 that are composed of a heavy-chain variable region connected by a flexible linker to the corresponding light-chain variable region...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1992
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3075 |
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