Independent domain folding of Pseudomonas exotoxin and single-chain immunotoxins: influence of interdomain connections.
We have studied the refolding of completely unfolded and reduced Pseudomonas exotoxin (PE) and of recombinant single-chain immunotoxins made with monoclonal antibody B3 that are composed of a heavy-chain variable region connected by a flexible linker to the corresponding light-chain variable region...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1992
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3075 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|