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Interstitial Infusion of Glioma-Targeted Recombinant Immunotoxin 8H9scFv-PE38
PURPOSE: Monoclonal antibodies (MAbs) have the potential to target therapy for high-grade gliomas. MAb 8H9 is specific for membrane protein B7H3 and is reactive with the majority of human high-grade gliomas. We tested the 8H9scFv-PE38 recombinant Pseudomonas-immunotoxin in a preclinical model of hig...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077038/ https://ncbi.nlm.nih.gov/pubmed/20371725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0996 |
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