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Recombinant Immunotoxin 4D5scFv-PE40 for Targeted Therapy of HER2-Positive Tumors

Recombinant immunotoxins are extremely promising agents for the targeted therapy of tumors with a certain molecular profile. In this work, we studied the properties of a new recombinant HER2-specific immunotoxin composed of the scFv antibody and a fragment of Pseudomonas exotoxin A (4D5scFv-PE40). H...

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Detalles Bibliográficos
Publicado en:Acta Naturae
Autores principales: Sokolova, E. A., Stremovskiy, O. A., Zdobnova, T. A., Balalaeva, I. V., Deyev, S. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: A.I. Gordeyev 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717253/
https://ncbi.nlm.nih.gov/pubmed/26798495
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