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Resampling to Address the Winner's Curse in Genetic Association Analysis of Time to Event

The “winner's curse” is a subtle and difficult problem in interpretation of genetic association, in which association estimates from large‐scale gene detection studies are larger in magnitude than those from subsequent replication studies. This is practically important because use of a biased e...

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Détails bibliographiques
Publié dans:Genet Epidemiol
Auteurs principaux: Poirier, Julia G., Faye, Laura L., Dimitromanolakis, Apostolos, Paterson, Andrew D., Sun, Lei, Bull, Shelley B.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609263/
https://ncbi.nlm.nih.gov/pubmed/26411674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21920
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