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Resampling to Address the Winner's Curse in Genetic Association Analysis of Time to Event

The “winner's curse” is a subtle and difficult problem in interpretation of genetic association, in which association estimates from large‐scale gene detection studies are larger in magnitude than those from subsequent replication studies. This is practically important because use of a biased e...

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Bibliografiske detaljer
Udgivet i:Genet Epidemiol
Main Authors: Poirier, Julia G., Faye, Laura L., Dimitromanolakis, Apostolos, Paterson, Andrew D., Sun, Lei, Bull, Shelley B.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609263/
https://ncbi.nlm.nih.gov/pubmed/26411674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21920
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