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Fast and Accurate Shared Segment Detection and Relatedness Estimation in Un-phased Genetic Data via TRUFFLE
Relationship estimation and segment detection between individuals is an important aspect of disease gene mapping. Existing methods are either tailored for computational efficiency or require phasing to improve accuracy. We developed TRUFFLE, a method that integrates computational techniques and stat...
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| Publicat a: | Am J Hum Genet |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6612710/ https://ncbi.nlm.nih.gov/pubmed/31178127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.05.007 |
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